PUVA-induced phototoxicity: Incidence and causes - 11/09/11
Abstract |
Background: Phototoxicity is the most significant short-term adverse effect of PUVA therapy.
Objective: We attempted to determine the incidence and possible causes of phototoxicity of sufficient degree to cause interruption of treatment.
Methods: A retrospective study was conducted of 16,506 PUVA treatments given to 414 patients in two treatment centers.
Results: Phototoxicity occurred in 10.9% of patients and was an adverse effect in 0.3% of treatments. Problems with the treatment protocol were the main cause.
Conclusion: Phototoxicity is a common adverse effect, and patients should be warned of this potential occurrence. Awareness of the causes may help to reduce the incidence of this problem.
(J Am Acad Dermatol 1997;36:183-5.)
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Vol 36 - N° 2
P. 183-186 - février 1997 Retour au numéro
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