Localized scleroderma in breast cancer patients treated with supervoltage external beam radiation: Radiation port scleroderma - 11/09/11

Doi : 10.1016/S0190-9622(96)90116-4

Daniel A Davis, MD ^⁎,^1,², Philip R Cohen, MD ^2,^3,^5,⁶, Marcia D McNeese, MD ^5,⁶, Madeleine Duvic, MD ^2,^4,^5,⁶
^a From the Department of Dermatology, University of Texas, Medical Branch, Galveston, Texas, USA
^b the Department of Dermatology, University of Texas, Houston, Texas, USA
^c the Department of Pathology, University of Texas, Houston, Texas, USA
^d the Department of Internal Medicine, University of Texas, Houston, Texas, USA
^e the Department of Medical Specialties, Section of Dermatology, University of Texas M. D. Anderson Cancer Center, Houston, Texas, USA
^f Department of Radiation Oncology, University of Texas M. D. Anderson Cancer Center, Houston, Texas, USA

¹Reprint requests: Daniel A. Davis, MD, University of Texas Medical Branch, Department of Dermatology, 301 University, McCullough Bldg., Suite 4.112, Galveston, TX 77555.

Abstract

Background: An association between systemic scleroderma, radiation, and breast cancer has been recognized. However, localized scleroderma in the radiation port of breast cancer patients has been rarely described.

Objective: Our purpose was to describe the concurrence of localized scleroderma, supervoltage radiation, and breast carcinoma.

Methods: Patients were prospectively evaluated in a tertiary care cancer center, and the literature was reviewed.

Results: We describe six patients with breast cancer in whom localized scleroderma developed within their radiation port.

Conclusion: Radiation port localized scleroderma can be a sequela of supervoltage radiation therapy in patients with breast cancer. Recognition is important because localized scleroderma can clinically mimic recurrent breast carcinoma.

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Vol 35 - N° 6

P. 923-927 - décembre 1996 Retour au numéro

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Localized scleroderma in breast cancer patients treated with supervoltage external beam radiation: Radiation port scleroderma - 11/09/11

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