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Médecine et maladies infectieuses
Volume 37, n° 7-8
pages 422-434 (juillet-août 2007)
Doi : 10.1016/j.medmal.2006.01.026
Received : 15 January 2006 ;  accepted : 15 January 2006
Aspects articulaires, musculaires, cardiaques et autres manifestations potentielles au cours de la maladie de Lyme
Lyme arthritis, Lyme carditis and other presentations potentially associated to Lyme disease

E. Begon
Service de dermatologie, centre hospitalier général René-Dubos, 6, avenue de l'Île-de-France, BP 79, 95303 Cergy-Pontoise cedex, France 


La maladie de Lyme ou borréliose de Lyme, impliquant les spirochètes du groupe Borrelia burgdorferi , est la plus fréquente zoonose transmise par les tiques dans l'hémisphère Nord. L'infection débute habituellement par une lésion cutanée caractéristique, l'érythème chronique migrant. Les patients peuvent ultérieurement présenter des manifestations cardiaques, articulaires ou neurologiques. Certains patients persistent à présenter des symptômes non spécifiques après un traitement antibiotique bien conduit. La persistance de ces symptômes après traitement a reçu l'appellation de «maladie de Lyme chronique». Dans le cadre de la première conférence de consensus française sur la maladie de Lyme, l'ensemble des aspects des atteintes cardiaques et articulaires sont décrits après synthèse de la littérature récente. Les preuves de l'implication de Borrelia dans la maladie de Lyme chronique et d'autres pathologies sont discutées.

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Lyme disease or Lyme borreliosis is the most common tick-transmitted disease in the Northern hemisphere and is caused by Borrelia burgdorferi spirochetes. Lyme disease commonly begins with a characteristic skin lesion, erythema migrans. Weeks or months later, the patients may have neurologic, joint, or cardiac abnormalities. Some patients may still present persistent deep fatigue and various unspecific symptoms after standard courses of antibiotic treatment for Lyme disease. This constellation of symptoms has been variously referred to as "chronic Lyme disease", or "post-Lyme disease syndrome". The first French National Consensus Conference on Lyme Disease was the reason to review all aspects of articular and cardiac manifestations of Lyme disease after a synthesis of recent literature. The involvement of Borrelia species in chronic Lyme disease and other pathologies is discussed.

The full text of this article is available in PDF format.

Mots clés : Arthrite de Lyme, Cardite de Lyme, Maladie de Lyme chronique

Keywords : Lyme arthritis, Lyme carditis, Chronic Lyme disease

© 2007  Published by Elsevier Masson SAS.
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