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Archives de pédiatrie
Volume 14, n° S3
pages 156-158 (octobre 2007)
Doi : S0929-693X(07)80020-0
Rotavirus: une infection ubiquitaire?
Rotavirus: an ubiquitous infection?
 

M. Bellaiche, J. Viala, V. Degas, J.-P. Cézard
Service de Gastro-entérologie, Nutrition et Mucoviscidose, Hôpital Robert Debré, 48 bd Sérurier 75019 Paris, France 

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Résumé

Le rotavirus est l'agent pathogène retrouvé le plus fréquemment dans les gastro-entérites de l'enfant. Une phase virémique est observée, dans 19 à 63 % des cas, au cours des 3 premiers jours d'infection, suggérant que le passage sanguin du rotavirus existe de manière fugace chez l'enfant immunocompétent. Une fois dans le sang, le rotavirus est en mesure d'atteindre de nombreux organes : foie (1/3 de perturbations du brian biologique hépatique), système nerveux central (2 % des encéphalites virales aurait pour origine le rotavirus), plus rarement les ganglions mésentériques ou les poumons. Toutefois, le lien d'imputabilité entre l'infection digestive à rotavirus et des manifestations systémiques sévères n'a pas été clairement établi. D'autres études sont nécessaires avant d'affirmer la responsabilité du rotavirus dans ces désordres viscéraux sévères.

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Abstract
Abstract

Rotavims is the most frequent virus found in childhood gastro enteritis. A rotavirus viremia is observed in 19 to 63 % of cases, for three days at the beginning of infection. Then, rotavirus can reach several organs as liver (hepatitis in 1/3 of case), nervous central system (2 % of encephalitis could be linked to rotavims), or more infrequently mesenteric lymph nodes, lung or heart. However, the link between rotavirus and systemic manifestations has not been well established. Further studies are necessary to confirm the role of rotavirus in these organ's lesions.

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Mots clés : Rotavirus, Diarrhée




© 2007  Published by Elsevier Masson SAS.
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