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Journal of the American Academy of Dermatology
Volume 66, n° 4
pages 535.e1-535.e16 (avril 2012)
Doi : 10.1016/j.jaad.2011.11.961
Continuing Medical Education

Graft-versus-host disease : Part II. Management of cutaneous graft-versus-host disease

Sharon R. Hymes, MD a, , Amin M. Alousi, MD b, Edward W. Cowen, MD, MHSc c
a Department of Dermatology, University of Texas MD Anderson Cancer Center, Houston, Texas 
b Department of Stem Cell Transplantation and Cellular Therapy, University of Texas MD Anderson Cancer Center, Houston, Texas 
c Dermatology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 

Correspondence to: Sharon R. Hymes, MD, Department of Dermatology, University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd-434, Houston, TX 77030-4009.

Dermatologists are ideally suited to manage the various cutaneous sequelae of graft-versus-host disease (GVHD) outlined in part I of this review. However, the complexity of the patient with GVHD, including comorbidities, potential drug interactions related to polypharmacy, and the lack of evidence-based treatment guidelines, are significant challenges to optimizing patient care. In this section, we will provide an outline for the role of the dermatologist in a multispecialty approach to caring for patients with GVHD.

The full text of this article is available in PDF format.

Key words : cyclosporine, extracorporeal photopheresis, graft-versus-host disease, hematopoietic cell transplantation, imatinib mesylate, mycophenolate mofetil, phototherapy, tacrolimus, rituximab

Abbreviations used : CNI, CSA, ECP, EV, GVHD, GVT, HCT, MMF, MSC, mTOR, MTX, NB-UVB, PUVA, PDGFR, SCC, TSS, UVA-1, UVR, Tregs, TSS

 Supported in part by the Intramural Research Program of the National Cancer Institute, Center for Cancer Research.
 Reprints not available from the authors.

  No longer available.

© 2011  American Academy of Dermatology, Inc.@@#104156@@
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