Article

1 Iconography
Access to the text (HTML) Access to the text (HTML)
PDF Access to the PDF text
Advertising


Access to the full text of this article requires a subscription.
  • If you are a subscriber, please sign in 'My Account' at the top right of the screen.

  • If you want to subscribe to this journal, see our rates

  • You can purchase this item in Pay Per ViewPay per View - FAQ : 30,00 € Taxes included to order
    Pages Iconography Videos Other
    4 1 0 0


Archives de pédiatrie
Volume 19, n° 4
pages 404-407 (avril 2012)
Doi : 10.1016/j.arcped.2012.01.011
Received : 22 Mars 2011 ;  accepted : 16 January 2012
L’infection néonatale à Sténotrophomonas maltophilia à propos de 2 cas
Neonatal infection with Stenotrophomonas maltophilia (2 case studies)
 

S. Issaoui a, b , F.M.R. Maoulainine a, , b, N.S. Elidrissi a, b, N. Sorra c, L. Chabaa c, A. Aboussad a, b
a Service de réanimation néonatale, hôpital Mère-Enfant, CHU Mohamed VI, Marrakech, Maroc 
b Unité de recherche l’enfance, la santé et le développement, faculté de médecine et de pharmacie, université Cadi Ayyad, Marrakech, Maroc 
c Laboratoire d’analyses médicales, hôpital Mère-Enfant, CHU Mohamed VI, Marrakech, Maroc 

Auteur correspondant.
Résumé

Sténotrophomonas maltophilia (S.M.) est un bacille Gram-négatif naturellement résistant aux céphalosporines et aux carbapénèmes qui peut coloniser différents sites et être responsable d’infections graves dont le traitement constitue un défi. Nous rapportons 2 cas d’infection nosocomiale par S.M. chez 2 nouveau-nés. L’un, âgé de 3j, avait présenté une infection à point de départ respiratoire traitée par ciprofloxacine et compliquée d’un choc septique fatal. L’autre, âgé de 11j, avait présenté un empyème et des abcès cérébraux traités avec succès par l’association amikacine-chloramphénicol. Certaines études épidémiologiques rapportent que S.M. est le 2e bacille Gram-négatif responsable d’infections nosocomiales néonatales après Klebsiella pneumoniae . L’atteinte du parenchyme cérébral est une localisation rare chez le nouveau-né, alors que la localisation respiratoire est habituelle. Devant la multirésistance de ce germe aux antibiotiques, le choix du traitement est parfois difficile. Ces 2 cas d’infections à S.M. rappellent l’émergence de ce germe et sa multirésistance naturelle aux antibiotiques.

The full text of this article is available in PDF format.
Summary
Introduction

Stenotrophomonas maltophilia (S.M.) is a Gram-negative bacillus, naturally resistant to cephalosporins and carbapenems, which can colonize different sites and may be responsible for serious infections for which treatment is a real challenge. We report 2 cases of nosocomial S.M. infection in 2 hospitalized newborns in the neonatal intensive care unit.

Case 1

A 3-day-old newborn presented with infection beginning in the respiratory system, treated with ciprofloxacin, and complicated by septicemia, resulting in death.

Case 2

An 11-day-old newborn presented with brain S.M. suppuration: empyema and multiple abscesses were treated successfully with the combination of amikacin and chloramphenicol with good progression in the short and medium terms.

Discussion

Some epidemiological studies report that S.M. is the second Gram-negative bacillus responsible for nosocomial infection after Klebsiella pneumoniae . While the respiratory location of the bacterium is typical, cerebral parenchyma damage is rare in the newborn. The treatment remains very delicate and difficult because of this bacterium’s drug multiresistance.

Conclusion

These 2 cases of infection caused by S.M. including respiratory tract infection with bacteremia and cerebral suppuration in newborns have broadened the spectrum of diseases caused by this organism and are a reminder of the emergence of this organism and its natural resistance to several antibiotics.

The full text of this article is available in PDF format.


© 2012  Elsevier Masson SAS. All Rights Reserved.
EM-CONSULTE.COM is registrered at the CNIL, déclaration n° 1286925.
As per the Law relating to information storage and personal integrity, you have the right to oppose (art 26 of that law), access (art 34 of that law) and rectify (art 36 of that law) your personal data. You may thus request that your data, should it be inaccurate, incomplete, unclear, outdated, not be used or stored, be corrected, clarified, updated or deleted.
Personal information regarding our website's visitors, including their identity, is confidential.
The owners of this website hereby guarantee to respect the legal confidentiality conditions, applicable in France, and not to disclose this data to third parties.
Close
Article Outline