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Annales de Dermatologie et de Vénéréologie
Volume 139, n° S2
pages 53-57 (avril 2012)
Doi : 10.1016/S0151-9638(12)70111-4
Dépression et psoriasis
Depression and psoriasis

L. Misery a, b
a Université de Bretagne Occidentale, Laboratoire des Neurosciences de Brest, France 
b CHU de Brest, Service de Dermatologie, 5, avenue Foch, 29200 Brest, France 


Si la co-morbidité psychiatrique est importante au cours du psoriasis, la dépression est de loin la maladie psychiatrique la plus fréquemment rencontrée. Il est donc important de la dépister et de la traiter. Les liens entre psoriasis et dépression ne sont pas uniquement psychopathologiques. Des facteurs biologiques peuvent aussi expliquer cette association. Il existe un cercle vicieux psoriasis-altération de la qualité de vie-dépression, mais l’amélioration du psoriasis n’entraîne pas forcément une amélioration de la dépression. A contrario , il est bien évident qu’un patient dépressif traitera moins bien son psoriasis.

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Psychiatric co-morbidity is very frequently associated with psoriasis and depression is observed in numerous patients with psoriasis. Early detection and treatment are very important. The links between psoriasis and depression are not only psychopathological. Biological factors could also explain this association. There is a vicious circle psoriasisalteration of quality of life-depression, but psoriasis improvement is not always followed by an improvement of depression. A contrario , it is obvious that a depressive patient has a bad observance of treatment.

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Mots clés : Dépression, Psoriasis, TNF, Alexithymie, Psychose maniacodépressive, Qualité de vie

Keywords : Depression, Psoriasis, TNF, Alexithymia, Bipolar disorder, Quality of life

© 2012  Elsevier Masson SAS. All Rights Reserved.
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