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Archives of cardiovascular diseases
Volume 105, n° 4
pages 226-238 (avril 2012)
Doi : 10.1016/j.acvd.2011.11.005
Received : 27 July 2011 ;  accepted : 16 November 2011
Rate versus rhythm control in atrial fibrillation and clinical outcomes: Updated systematic review and meta-analysis of randomized controlled trials
Contrôle de la fréquence ou du rythme cardiaque dans la fibrillation atriale : méta-analyse des études randomisées contrôlées
 

Figure 1




Figure 1 : 

Flowchart of study selection for meta-analysis. AF: atrial fibrillation; CENTRAL: Cochrane Central Register of Controlled Trials; RCTs: randomized controlled trials.


Figure 2




Figure 2 : 

Forest plot for all-cause mortality. AFFIRM: Atrial Fibrillation Follow-up Investigation of Rhythm Management study; AF-CHF: Atrial Fibrillation and Congestive Heart Failure study; CAFÉ-II: controlled study of rate versus rhythm control in patients with chronic atrial fibrillation and heart failure; CI: confidence interval; HOT CAFÉ: How to Treat Chronic Atrial Fibrillation study; J-RHYTHM: Japanese Rhythm Management Trial for Atrial Fibrillation; M-H: Mantel-Haenszel; PIAF: Pharmacological Intervention in Atrial Fibrillation study; RACE: Rate Control versus Electrical Cardioversion for Persistent Atrial Fibrillation study; STAF: Strategies of Treatment of Atrial Fibrillation study.


Figure 3




Figure 3 : 

Forest plot for cardiovascular mortality. AFFIRM: Atrial Fibrillation Follow-up Investigation of Rhythm Management study; AF-CHF: Atrial Fibrillation and Congestive Heart Failure study; CAFÉ-II: controlled study of rate versus rhythm control in patients with chronic atrial fibrillation and heart failure; CI: confidence interval; HOT CAFÉ: How to Treat Chronic Atrial Fibrillation study; M-H: Mantel-Haenszel; PIAF: Pharmacological Intervention in Atrial Fibrillation study; RACE: Rate Control versus Electrical Cardioversion for Persistent Atrial Fibrillation study; STAF: Strategies of Treatment of Atrial Fibrillation study.


Figure 4




Figure 4 : 

Forest plot for arrhythmic/sudden death mortality. AFFIRM: Atrial Fibrillation Follow-up Investigation of Rhythm Management study; AF-CHF: Atrial Fibrillation and Congestive Heart Failure study; CI: confidence interval; M-H: Mantel-Haenszel; PIAF: Pharmacological Intervention in Atrial Fibrillation study; RACE: Rate Control versus Electrical Cardioversion for Persistent Atrial Fibrillation study; STAF: Strategies of Treatment of Atrial Fibrillation study.


Figure 5




Figure 5 : 

Forest plot for ischaemic stroke. AFFIRM: Atrial Fibrillation Follow-up Investigation of Rhythm Management study; CI: confidence interval; HOT CAFÉ: How to Treat Chronic Atrial Fibrillation study; J-RHYTHM: Japanese Rhythm Management Trial for Atrial Fibrillation; M-H: Mantel-Haenszel; STAF: Strategies of Treatment of Atrial Fibrillation study.


Figure 6




Figure 6 : 

Forest plot for systemic embolism. AFFIRM: Atrial Fibrillation Follow-up Investigation of Rhythm Management study; AF-CHF: Atrial Fibrillation and Congestive Heart Failure study; CI: confidence interval; HOT CAFÉ: How to Treat Chronic Atrial Fibrillation study; J-RHYTHM: Japanese Rhythm Management Trial for Atrial Fibrillation; M-H: Mantel-Haenszel; PIAF: Pharmacological Intervention in Atrial Fibrillation study; RACE: Rate Control versus Electrical Cardioversion for Persistent Atrial Fibrillation study; STAF: Strategies of Treatment of Atrial Fibrillation study.


Figure 7




Figure 7 : 

Forest plot for major bleeding. AFFIRM: Atrial Fibrillation Follow-up Investigation of Rhythm Management study; CI: confidence interval; HOT CAFÉ: How to Treat Chronic Atrial Fibrillation study; J-RHYTHM: Japanese Rhythm Management Trial for Atrial Fibrillation; M-H: Mantel-Haenszel; RACE: Rate Control versus Electrical Cardioversion for Persistent Atrial Fibrillation study; STAF: Strategies of Treatment of Atrial Fibrillation study.

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