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Journal of the American Academy of Dermatology
Volume 62, n° 6
pages 1045-1049 (juin 2010)
Doi : 10.1016/j.jaad.2009.06.054
Case & Reviews

595-nm long pulsed dye laser and 1450-nm diode laser in combination with intralesional triamcinolone/5-fluorouracil for hypertrophic scarring following a phenol peel
 

Tracy M. Katz, MD a, Adrienne S. Glaich, MD b, Leonard H. Goldberg, MD a, c, Paul M. Friedman, MD a, c, d,
a DermSurgery Associates, Houston, Texas 
b Baylor College of Medicine, Houston, Texas 
c Department of Dermatology, Weill Cornell Medical College, Methodist Hospital, Houston, Texas 
d The University of Texas Medical School, Houston, Texas 

Reprint requests: Paul M. Friedman, MD, 7515 Main St, Suite 210, Houston, TX 77030.
Abstract

Hypertrophic scars and keloids are a therapeutic challenge because of the low response to treatment and recurrences after treatment. A variety of treatment regimens have been used with different degrees of success, with no universally accepted treatment protocol resulting in their complete and permanent resolution. We offer this case to demonstrate a combination approach for the treatment of hypertrophic scarring. A 75-year-old woman (with Fitzpatrick skin type II) presented with a 4-month history of scarring, which had developed following a phenol peel for perioral rhytides. The patient underwent 10 treatment sessions with the 595-nm long-pulsed dye laser followed immediately by the 1450-nm diode laser in combination with intralesional triamcinolone and 5-fluorouracil. After the fifth treatment session, about 90% improvement was noted; at the last treatment session, greater than 95% overall improvement was noted. Two and a half years after the last treatment session, the patient and treating physician noted no regression. A limitation of this therapy is that the combination approach makes it difficult to determine what individual contributions each treatment modality had on the final result. We have illustrated a successful multifaceted treatment regimen for hypertrophic scars and keloids using a combination approach.

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Abbreviations used : 5-FU, IL-TAC, PDL, UV



 Funding sources: None.
 Conflicts of interest: None declared.



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