Prevalence and factors associated with hidradenitis suppurativa: Results from two case-control studies - 24/04/13

Doi : 10.1016/j.jaad.2008.06.020

Jean E. Revuz, MD, PhD ^a,^b,^⁎, Florence Canoui-Poitrine, MD ^b,^c, Pierre Wolkenstein, MD, PhD ^a,^b, Cedric Viallette, MSc ^d, Germaine Gabison, MD ^a, Florence Pouget, MD ^a, Florence Poli, MD ^a, Ousmane Faye, MD ^g, Jean Claude Roujeau, MD, PhD ^a,^b, Genevieve Bonnelye, MSc ^e, Jean Jacques Grob, MD, PhD ^f, Sylvie Bastuji-Garin, MD, PhD ^b,^c
^a AP-HP, Groupe Henri-Mondor Albert-Chenevier, Service de Dermatologie, Creteil, France
^c Service de Santé Publique, Creteil, France
^d Unite de Recherche Clinique, Creteil, France
^b Universite Paris 12, Faculte de Medecine, Creteil, France
^e TNS Sofres Institute, Montrouge, France
^f Dermatology Department, Hospital Sainte Marguerite, Marseille, France
^g Dermatology Department; CNAM-Ex Institut Marchoux, Bamako, Mali

Reprint requests: Jean E. Revuz, MD, PhD, Dermatology Departement, Universite Paris XII, Hopital Henri Mondor, 51 avenue du Marechal DeLattre de Tassigny, 94010 Creteil, France.

Abstract

Background

Conflicting opinions have been reported regarding the epidemiology of hidradenitis suppurativa.

Objective

We sought to evaluate the prevalence of hidradenitis suppurativa and to identify associated factors.

Methodology

Prevalence was evaluated using a representative sample of the French population (n = 10,000). Associated risk factors were assessed using two case-control studies, one population-based with 67 self-reported patients and 200 control subjects, and the other clinic-based with 302 medically assessed patients and 906 control subjects.

Results

The prevalence was 1% of the French population. Multivariate analyses showed a strong association with current smoking in self-reported (odds ratio = 4.16, 95% confidence interval [2.99-8.69]) and in medically assessed (odds ratio = 12.55 [8.58-18.38]) populations. Association with body mass index was significant in medically assessed patients (odds ratio = 1.12 [1.08-1.15]) for each increase of 1 U of BMI.

Limitations

A causal relationship could not be established with such a cross-sectional study.

Conclusion

Hidradenitis suppurativa is a common disease, frequently associated with smoking and being overweight.

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Abbreviations used : BMI, HS, OR

Plan

Methods

Survey sample

Case-control studies

Population-based case-control study

Clinic-based case-control study

Factors associated with HS

Medically assessed patients compared with control subjects

Discussion

	Funding sources: None.
	Conflicts of interest: None declared.

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Vol 59 - N° 4

P. 596-601 - octobre 2008 Retour au numéro

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Prevalence and factors associated with hidradenitis suppurativa: Results from two case-control studies - 24/04/13

Abstract

Background

Objective

Methodology

Results

Limitations

Conclusion

Plan

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