Silver treatments and silver-impregnated dressings for the healing of leg wounds and ulcers: A systematic review and meta-analysis - 24/04/13
Abstract |
Previous systematic reviews of silver-impregnated dressings have been contradictory regarding the healing of leg wounds/ulcers. Our systematic review was restricted to randomized controlled trials. Cochrane Library, Scopus, and MEDLINE databases were searched using the term “silver” in combination with “wound” or “ulcer” (and plural versions) without date/language restriction. Study quality was assessed and meta-analysis conducted for complete wound healing, wound size reduction, and healing rates. Overall study quality was fair with most studies having some bias. Evidence for wound healing using individual studies was poor. Meta-analyses found strong evidence for wound healing based on wound size reduction but no evidence based on complete wound-healing or healing rates. Although our results provide some evidence that silver-impregnated dressings improve the short-term healing of wounds and ulcers, long-term effects remain unclear. Clinical trial data with longer follow-up times are needed to address these issues.
Le texte complet de cet article est disponible en PDF.Key words : meta-analysis, silver-impregnated dressing, silver treatment, subgroup analysis, systematic review
Abbreviations used : CI, RCT, WMD
Plan
Funding sources: None. |
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Disclosure: Dr Carter is a speaker for Hollister Wound Care LLC. Ms Tingley-Kelley and Dr Warriner have no conflicts of interest to declare. |
Vol 63 - N° 4
P. 668-679 - octobre 2010 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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