Disease severity, scratching, and sleep quality in patients with atopic dermatitis - 24/04/13
Abstract |
Background |
The relationship between sleep quality and disease severity in patients with atopic dermatitis has not been clearly defined.
Methods |
Sleep efficiency and scratching were measured over 2 nights by polysomnography, actigraphy, and self-report in 20 adults with atopic dermatitis. Tumor necrosis factor, interleukin (IL)-6, and IL-10 were assayed from a subset of 9 participants.
Results |
Sleep measured by actigraphy and polysomnography were strongly associated with each other. Decreased sleep efficiency was associated with increasing disease severity, scratching, and IL-6. Self-reported sleep quality and quality of life were not significantly correlated with either objective sleep measure.
Limitations |
Results in this pilot study await confirmation in a larger investigation.
Conclusion |
Objective measures but not self-report documented that increasing severity of atopic dermatitis results in more scratching and declining sleep quality. Our data also suggest an important relationship between sleep and IL-6.
Le texte complet de cet article est disponible en PDF.Abbreviations used : AD, IL, PSG, REM, TBSA
Plan
Funding sources: None. |
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Conflicts of interest: None declared. |
Vol 58 - N° 3
P. 415-420 - mars 2008 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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