Reactive nonsexually related acute genital ulcers: Review of cases evaluated at Mayo Clinic - 24/04/13
, David A. Wetter, MD a, Sara B. Ferguson, MD b, Roy S. Rogers, MD b
Reprint requests: Alison J. Bruce, MB, ChB, Department of Dermatology, Mayo Clinic, 200 First St SW, Rochester, MN 55905.Abstract |
Background |
Reactive nonsexually related acute genital ulcers (RNSRAGU) occur in pubertal girls after an acute systemic infection.
Objective |
We sought to characterize RNSRAGU by reviewing the medical records of patients with this disorder.
Methods |
We searched our medical index database from 1997 to 2007 for RNSRAGU cases. Questionnaires were mailed to identified patients.
Results |
The study included 10 patients; 5 responded to the questionnaire. The mean age at onset was 11.5 years. Vulvar ulcers were preceded by viral gastroenteritis (n = 3), viral upper respiratory tract infection (n = 3), streptococcal pharyngitis (n = 1), influenza (n = 1), and other nonspecific febrile illnesses (n = 2). Seven patients had oral involvement also; 6 had at least one recurrence; and 3 were hospitalized for pain control. Analgesics and topical corticosteroids were the most common treatments. Ulcerations resolved within several weeks in all patients.
Limitations |
Retrospective study design, small study size, and 50% questionnaire response rate are limitations.
Conclusions |
Although rare, RNSRAGU should be considered when genital ulceration follows an acute systemic illness.
Le texte complet de cet article est disponible en PDF.Key words : genital ulcers, Lipschütz ulcer, ulcus vulvae acutum
Abbreviations used : EBV, HSV, PCR, RNSRAGU
Plan
| Funding sources: None. |
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| Conflicts of interest: None declared. |
Vol 63 - N° 1
P. 44-51 - juillet 2010 Retour au numéro
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