4 Iconography
Access to the text (HTML) Access to the text (HTML)
PDF Access to the PDF text

Access to the full text of this article requires a subscription.
  • If you are a subscriber, please sign in 'My Account' at the top right of the screen.

  • If you want to subscribe to this journal, see our rates

Journal of the American Academy of Dermatology
Volume 63, n° 5
pages 805-814 (novembre 2010)
Doi : 10.1016/j.jaad.2009.08.066
accepted : 3 August 2009
Original Articles

Nevus simplex: A reconsideration of nomenclature, sites of involvement, and disease associations

Anna M. Juern, MD a, Zoey R. Glick, MD b, Beth A. Drolet, MD a, Ilona J. Frieden, MD c,
a Medical College of Wisconsin, Milwaukee, Wisconsin 
b George Washington University Medical School, Washington, DC 
c University of California, San Francisco, California 

Reprint requests: Ilona J Frieden, MD, University of California, San Francisco, Department of Dermatology, Box 0316, San Francisco, CA 94143-0316.

Nevus simplex (NS) is a common birthmark on the forehead, glabella, upper eyelids, and nape. More widespread involvement can be confused with port-wine stains (nevus flammeus) and other vascular birthmarks.


To further categorize the anatomic locations in infants with extensive NS and evaluate for any possible disease associations.


We conducted a retrospective review of patients with extensive NS seen at two tertiary care centers.


Twenty-seven patients with extensive NS were identified. All had at least one typical site of involvement: glabella (77.8%), nape (59.3%), and eyelids (55.6%). Additional sites were the scalp, including the vertex, occiput, parietal (66.7%); nose (66.7%); lip (59.2%); lumbosacral skin (55.6%); and upper and mid back (14.8 %).


Retrospective nature of the study and relatively small sample size.


We propose the term “nevus simplex complex” for NS with more widespread involvement beyond the typical sites. Consistent use of the term “nevus simplex” will aid in correct diagnosis and appropriate management of these birthmarks.

The full text of this article is available in PDF format.

Abbreviations used : BWS, IH, NS

 Funding sources: None.
 Conflicts of interest: None declared.

  Unpublished observations, Ilona Frieden, April 2009.

© 2009  American Academy of Dermatology, Inc.@@#104156@@
EM-CONSULTE.COM is registrered at the CNIL, déclaration n° 1286925.
As per the Law relating to information storage and personal integrity, you have the right to oppose (art 26 of that law), access (art 34 of that law) and rectify (art 36 of that law) your personal data. You may thus request that your data, should it be inaccurate, incomplete, unclear, outdated, not be used or stored, be corrected, clarified, updated or deleted.
Personal information regarding our website's visitors, including their identity, is confidential.
The owners of this website hereby guarantee to respect the legal confidentiality conditions, applicable in France, and not to disclose this data to third parties.
Article Outline
You can move this window by clicking on the headline