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Journal of the American Academy of Dermatology
Volume 63, n° 5
pages 882-885 (novembre 2010)
Doi : 10.1016/j.jaad.2009.06.045
Case & Reviews

Cutaneous collagenous vasculopathy with generalized telangiectasia in two female patients
 

Alfonso Perez, Mary E. Wain, MD, MRCP, Alistair Robson, MRCPath, Dip RCPath, Richard W. Groves, FRCP, Catherine M. Stefanato, MD, FRCPath
St John’s Institute of Dermatology, St Thomas’ Hospital, London, United Kingdom 

Reprint requests: C. M. Stefanato, MD, FRCPath, St John’s Institute of Dermatology, St Thomas’ Hospital, London SE1 7EH, UK.
Abstract

Cutaneous collagenous vasculopathy is characterized by generalized cutaneous telangiectasia and unique microscopic and ultrastructural vascular changes, consisting of marked collagen deposition within the vascular walls of the post-capillary venules in the superficial dermis. There are only 4 previous cases described in the medical literature, all in males, mostly middle-aged. We have recently seen two female patients with clinical and histopathologic features diagnostic of cutaneous collagenous vasculopathy, indicating that it is not restricted to males. As cutaneous collagenous vasculopathy can be clinically indistinguishable from generalized essential telangiectasia, and histopathologic studies are rarely performed for this condition, it is likely that cutaneous collagenous vasculopathy frequently passes unrecognized, but it may be more common than previously thought.

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 Funding sources: None.
 Conflicts of interest: None.



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