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Archives of cardiovascular diseases
Volume 106, n° 4
page 257 (avril 2013)
Doi : 10.1016/j.acvd.2013.03.032
Abstracts

Impact of segmental hypertrophy on global and regional left ventricular deformation in hypertrophic cardiomyopathy: A 3D speckle tracking imaging study
 

D. Voilliot a, O. Huttin a, T. Vaugrenard b, C. Selton-Suty a
a ILCV, CHU de Brabois, Nancy, France 
b CHU de Marseille, Marseille, France 

Objectives .– To assess LV myocardial deformation with 3D echocardiography in HCM and study the impact of hypertrophy on global and regional systolic deformation.

Patients and methods .– A complete rest echocardiography (GE Vivid 9) was performed in 41 HCM and in 114 control patients. Secondary HCM were excluded. LV systolic deformation was assessed by 3D strains. Values of 3D global LV longitudinal (3DGLS), circumferential (3DGCS), radial (3DRS) and area strain (3DGAS) were obtained from all patients. We classified segments depending on their thickness as first quartile (<105mm, n =157), second quartile (105–131mm, n =152), third quartile (131–166mm, n =162) and fourth quartile (>166mm, n =165).

Results .– All strain values were significantly higher in control than in HCM pts. There was a significant decrease from second quartile to fourth quartile (P <0.05), gradually for longitudinal then radial and circumferential strain values (Table 1).

Conclusion .– 3D echocardiography is a useful tool in HCM patients, bringing in one acquisition all global and regional deformations parameters.

Hypertrophy has an impact on the global mechanics of LV and on regional kinetics of hypertrophic segment impairing gradually longitudinal then circumferential and radial deformation. However, there is also an impact on mechanics of non-hypertrophic segments suggesting an overall involvement of the myocardium.


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