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Archives of cardiovascular diseases
Volume 106, n° 6-7
pages 349-356 (juin 2013)
Doi : 10.1016/j.acvd.2013.04.006
Received : 22 December 2012 ;  accepted : 9 April 2013
Impact of selective serotonin reuptake inhibitor therapy on heart valves in patients exposed to benfluorex: A multicentre study
Traitement par inhibiteurs sélectifs de recapture de la sérotonine et atteinte valvulaire cardiaque chez les patients exposés au benfluorex : une étude multicentrique

Figure 1

Figure 1 : 

Apical long-axis two-dimensional views magnified on the mitral valve in systole (A) and diastole (B), and colour Doppler flow mapping in systole (C), showing leaflet thickening associated with thickening and shortening of the chordae tendineae and retraction of one or both leaflets with reduced valve mobility, with a typical drumstick appearance, in a patient with mitral valve abnormalities suggestive of drug-induced valvular heart disease and moderate mitral regurgitation. MR: mitral regurgitation; MV: mitral valve.

Figure 2

Figure 2 : 

Parasternal long-axis two-dimensional views magnified on the aortic valve in systole (A) and diastole (B), and colour Doppler flow mapping in parasternal long-axis (C) and short-axis (D) views, showing central aortic regurgitation, leaflet thickening, presence of a small central triangular valve hiatus during diastole and presence of a subtle dome-like appearance of the aortic valve during systole, these abnormalities being suggestive of drug-induced valvular heart disease. AR: aortic regurgitation; AV: aortic valve.

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