A comparative study of the mini-punch grafting and hair follicle transplantation in the treatment of refractory and stable vitiligo - 14/03/14
, Moslem Safarpour, MD a, Mokhtar Mapar, MSc c, Mohammad Hosein Haghighizadeh, MSc bAbstract |
Background |
Some vitiligo lesions are resistant to all medical treatments.
Objective |
We sought to compare the efficacy of hair follicle transplantation and mini-punch grafting for the treatment of refractory vitiligo lesions.
Methods |
A total of 25 patients with stable and resistant vitiligo participated in the study. In each patient, a resistant vitiligo patch was divided into 2 equal parts. One part was treated with hair follicle transplantation and the other part with mini-punch grafting. Postsurgically, the recipient areas were exposed to narrowband ultraviolet B twice a week for 6 months. The diameter of the repigmentation around each graft was measured monthly.
Results |
At the end of the sixth month, 68% of follicle grafts, and 72% of mini-punch grafts, had repigmentation. The mean diameter of repigmentation around follicle grafts was 5 ± 1.7 mm and around punch grafts was 5.3 ± 1.6 mm. There was no significant difference between the 2 groups statistically (P = .18).
Limitations |
Small sample size and short time of follow-up are limitations.
Conclusions |
Because the results of the 2 methods are not statistically different and mini-punch grafting is much easier to do than follicular transplantation, we recommend mini-punch grafting to treat drug-resistant vitiligo.
Le texte complet de cet article est disponible en PDF.Key words : Ahvaz, grafting, hair follicle, punch, resistant, transplantation, vitiligo
Plan
| This study was Dr Safarpour's postgraduate thesis and supported by a grant from Jundishapur University of Medical Sciences to Dr M. A. Mapar. |
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| Conflicts of interest: None declared. |
Vol 70 - N° 4
P. 743-747 - avril 2014 Retour au numéro
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