Scoring nail psoriasis - 14/05/14
, Peter C.M. van de Kerkhof, MD, PhD a, Maarten T. Bastiaens, MD, PhD b, Leon G.J.M. Plusjé, MD c, Robert L. Baran, MD d, Marcel C. Pasch, MD, PhD aAbstract |
Background |
Scoring systems are indispensable in evaluating the severity of disease and monitoring treatment response.
Objective |
We sought to evaluate the competence of various nail psoriasis severity scoring systems and to develop a new scoring system.
Methods |
The authors conducted a prospective, observational, single-point study of 36 patients given the diagnosis of fingernail psoriasis. Seven scoring systems were evaluated: Nail Psoriasis Severity Index (NAPSI), modified NAPSI, target NAPSI, Psoriasis Nail Severity Score, Nail Area Severity, Baran, and Cannavò et al. All tools were correlated with the Physician Global Assessment. Obtained information was integrated into the Nijmegen–Nail psoriasis Activity Index tooL (N-NAIL), and interrater and intrarater reliability was assessed.
Results |
Physician Global Assessment showed an acceptable correlation with the scoring system designed by Baran (r = 0.735, P < .01) and the Psoriasis Nail Severity Score (r = 0.734, P < .01). Target NAPSI showed low correlation (r = 0.203, P > .05). The correlation between Physician Global Assessment and the N-NAIL was 0.861 (P < .01). Excellent agreement was found for the intrarater and interrater reliability of the N-NAIL.
Limitations |
Sample size was limited.
Conclusion |
An adequate nail psoriasis scoring system is needed, as studies of treatments for nail psoriasis are on the horizon. Clinical severity of nail psoriasis was best reflected by the N-NAIL, followed by the Baran system and the Psoriasis Nail Severity Score.
Le texte complet de cet article est disponible en PDF.Key words : assessment tool, nail psoriasis, Nail Psoriasis Severity Index, Nijmegen–Nail Psoriasis Activity Index Tool, psoriasis, scoring systems
Abbreviations used : ICC, NAPSI, N-NAIL, PGA
Plan
| Funded by Janssen-Cilag B.V. Janssen-Cilag B.V. played no role in the design and conduct of the study or in data collection, data management, data analysis, interpretation of the data, manuscript preparation, manuscript review, or manuscript approval. |
|
| Conflicts of interest: None declared. |
Vol 70 - N° 6
P. 1061-1066 - juin 2014 Retour au numéro
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