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Journal of the American Academy of Dermatology
Volume 71, n° 1
pages 133-140 (juillet 2014)
Doi : 10.1016/j.jaad.2014.02.012
accepted : 6 February 2014

Diet and psoriasis, part I: Impact of weight loss interventions

Maya Debbaneh, BA a, b, , Jillian W. Millsop, MD a, c, Bhavnit K. Bhatia, BA a, d, John Koo, MD a, Wilson Liao, MD a
a Department of Dermatology, University of California, San Francisco, California 
b University of California, Irvine, School of Medicine, Irvine, California 
c University of Utah School of Medicine, Salt Lake City, Utah 
d Rush Medical College, Rush University Medical Center, Chicago, Illinois 

Reprint requests: Maya Debbaneh, BA, Department of Dermatology, University of California, San Francisco, 515 Spruce St, San Francisco, CA 94118.

Please see the August and September issues for the second and third parts of this series .


One of the most frequently asked questions by patients with psoriasis is whether dietary changes can improve their condition. Included in this discussion is whether dietary weight loss can benefit their skin disease. Obesity has been associated with a proinflammatory state and several studies have demonstrated a relationship between body mass index and psoriasis severity. However, the question of whether weight loss interventions can impact psoriasis outcome is less clear. Here, we review the literature to examine the efficacy of weight loss interventions, both dietary and surgical, on psoriasis disease course.

The full text of this article is available in PDF format.

Key words : body mass index, diet, gastric bypass, nutrition, obesity, psoriasis, weight loss

Abbreviations used : BMI, IL, MCP, MDA, PASI, PASI 75, TNF

 Dr Liao is supported in parts by grants from National Institute of Arthritis and Musculoskeletal and Skin Diseases (R01AR065174, K08AR057763). There were no direct funding sources for this work.
 Disclosure: Dr Koo is a speaker for AbbVie and Leo. Dr Koo conducts research for Amgen, Janssen, Novartis, Photomedex, Galderma, Pfizer, and Merck. Dr Koo has no stocks, employment, or board memberships with any pharmaceutical company. None of the grants were directly related to this study. Ms Debbaneh, Dr Millsop, Ms Bhatia, and Dr Liao have no conflicts of interest to declare.
 Ms Debbaneh, Dr Millsop, and Ms Bhatia contributed equally to this work.

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