Reliability of Clinician Erythema Assessment grading scale - 17/09/14
Abstract |
Background |
Facial erythema is a clinical hallmark of rosacea and often causes social and psychological distress. Although facial erythema assessments are a common endpoint in rosacea clinical trials, their reliability has not been evaluated.
Objective |
The objective of this study was to evaluate the inter- and intrarater reliability of the Clinician's Erythema Assessment (CEA), a 5-point grading scale of facial erythema severity.
Methods |
Twelve board-certified dermatologists, previously trained on use of the scale, rated erythema of 28 rosacea subjects twice on the same day. Interrater and intrarater agreement was assessed with the intraclass correlation and κ statistic.
Results |
The CEA had high interrater reliability and good intrarater reliability with an overall intraclass correlation coefficient (ICC) for session 1 and session 2 of 0.601 and 0.576, respectively; the overall weighted κ statistic for session 1 and session 2 was 0.692.
Limitations |
Raters were experienced dermatologists and there may be a risk of recall bias.
Conclusion |
When used by trained raters, CEA is a reliable scale for measuring the facial erythema of rosacea.
Le texte complet de cet article est disponible en PDF.Key words : Clinician Erythema Assessment, erythema, rating scale, rosacea, scale validation
Plan
| Supported by Galderma Research and Development, Princeton, NJ, and Galderma Laboratories LP, Fort Worth, TX. |
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| Disclosure: Dr Tan has served as a consultant, investigator, speaker, and on advisory board, and has received grants and honoraria from Galderma. Drs Leoni and Liu are employees of Galderma Research and Development. Dr Leyden has served as a consultant and on advisory boards, and has received honoraria from Galderma, Allergan, Anacor, Unilever, Sol-Gel, and Acleris and has served as a consultant and received honoraria from Cutanea. |
Vol 71 - N° 4
P. 760-763 - octobre 2014 Retour au numéro
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