Promising alternative clinical uses of prostaglandin F2? analogs: Beyond the eyelashes - 14/03/15
Abstract |
Prostaglandin F2α analogs, commonly prescribed for glaucoma treatment, have been shown to induce side effects such as cutaneous hypertrichosis and hyperpigmentation. Therefore, these medications have theoretic applications in the treatment of alopecia and disorders of hypopigmentation. We reviewed the literature to find original studies assessing the use of prostaglandin F2α analogs in these settings. Studies and reports were analyzed in regards to androgenic alopecia, alopecia areata, chemotherapy-induced alopecia, vitiligo, and hypopigmented scarring. Based on the results of these studies, and consideration of pathophysiologic mechanism, the most promising applications for prostaglandin F2α analogs include androgenic alopecia, chemotherapy-induced alopecia, and alopecia areata concurrently treated with corticosteroids.
Le texte complet de cet article est disponible en PDF.Key words : alopecia areata, androgenic alopecia, bimatoprost, glaucoma, latanoprost, prostaglandin, prostaglandin F2α analog, travoprost, vitiligo
Plan
Funding sources: None. |
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Conflicts of interest: None declared. |
Vol 72 - N° 4
P. 712-716 - avril 2015 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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