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Journal of the American Academy of Dermatology
Volume 74, n° 2
pages 197-212 (février 2016)
Doi : 10.1016/j.jaad.2015.04.060
accepted : 22 April 2015
Continuing Medical Education

Neurocutaneous disease : Cutaneous neuroanatomy and mechanisms of itch and pain

Miguel Chuquilin, MD a, Yazan Alghalith, BA b, Kristen Heins Fernandez, MD c,
a Department of Neurology, University of Missouri, Columbia, Missouri 
b School of Medicine, University of Missouri, Columbia, Missouri 
c Department of Dermatology, University of Missouri, Columbia, Missouri 

Correspondence to: Kristen Heins Fernandez, MD, Department of Dermatology, 1 Hospital Dr, MA 111, Columbia, MO 65212.

Few sources of information exist regarding cutaneous innervation and how to apply this basic neurologic science to the clinical treatment of itch, as often performed on a daily basis by dermatologists. We address the types of nerve fibers that innervate the skin and their different components and discuss the similarities and differences between itch and pain. We hope that increased knowledge of this topic will improve the recognition and treatment of neuropathic itch.

The full text of this article is available in PDF format.

Key words : cutaneous innervation, itch, nerve fibers, neuroanatomy, pain, pruritogens

 Funding sources: None.
 Conflicts of interest: None declared.
 Date of release: February 2016
 Expiration date: February 2019

© 2015  Published by Elsevier Masson SAS.