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Anaesthesia Critical Care & Pain Medicine
Sous presse. Epreuves corrigées par l'auteur. Disponible en ligne depuis le vendredi 2 novembre 2018
Doi : 10.1016/j.accpm.2018.08.004
Perioperative pain and post-operative nausea and vomiting (PONV) management after day-case surgery: The SFAR-OPERA national study

Frédéric Aubrun a, , Claude Ecoffey b, Dan Benhamou c, Laurent Jouffroy d, Pierre Diemunsch e, Kristina Skaare f, Jean Luc Bosson f, Pierre Albaladejo f, g
a Department of anaesthesiology and intensive care medicine, hospices Civils de Lyon, Lyon Croix Rousse university hospital, HESPER 7425 research team, Claude-Bernard Lyon 1 University, 69004 Lyon, France 
b Department of anaesthesia and intensive care, CHU de Rennes, Inserm UMR 991 and CIC 1414, Rennes 1 university, 35033 Rennes, France 
c Department of anaesthesiology and intensive care medicine, groupe hospitalier et faculté de médecine Paris Sud, AP–HP, hôpital Bicêtre, 94270 Le Kremlin-Bicêtre, France 
d Rhéna clinique de Strasbourg, Maison médicale des 2 Rives. 67000 Strasbourg, France 
e Department of anaesthesiology and intensive care medicine, university hospital of Hautepierre, 67000 Strasbourg, France 
f Clinical investigation centre, Grenoble university hospital, ThEMAS, TIMC, UMR, CNRS 5525, university Grenoble-Alpes, 38700 Grenoble, France 
g Department of anaesthesia and intensive care medicine, Grenoble university hospital, 38700 Grenoble, France 

Corresponding author at: Department of anaesthesiology and intensive care medicine, hospices civils de Lyon, Lyon Croix Rousse university Hospital, 103, Grande rue de la Croix Rousse, 69004 Lyon, France.Department of anaesthesiology and intensive care medicine, hospices civils de LyonLyon Croix Rousse university Hospital103, Grande rue de la Croix RousseLyon69004France

Since pain and post-operative nausea and vomiting (PONV) are the main reasons for failed discharge after day-case surgery, assessing pain and PONV is important. The aim was to describe the perioperative pain and PONV management within selected day-case surgical procedures in France.


The OPERA trial was carried out on given days between December 2013 and December 2014. Each participating centre was required to fill out 3 separate questionnaires aiming at describing (1) protocols about pain and PONV, (2) patients’ characteristics and procedures, (3) analgesic and PONV practice patterns for selected procedures.


Over the two days of investigation in each of the 221 randomly selected healthcare institutions, 7382 patients were included, of whom 2144 patients above 12 years underwent one of 10 selected procedures. Among responding institutions, 40% [33;47] had a dedicated pain management written protocol. Combination of tramadol and paracetamol was the most commonly prescribed (78% [71;83] of centres). Oral morphine was prescribed in 59/199 (30% [23; 37]) centres, for home treatment in 25/59 (42% [30; 56]) centres. However, there was no standardised take-home analgesic and PONV strategies for selected surgical procedures at risk of moderate to severe pain. PONV management guidance after discharge was included in only 12 % of centres.


This survey demonstrates that practice patterns for pain treatment and PONV prophylaxis after ambulatory surgery vary among French centres and are not always in line with national guidelines. Strategies to improve practices and make them more homogeneous are necessary.

The full text of this article is available in PDF format.

Keywords : Day surgery, Pain, Nausea and vomiting, National study

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