Focal atrichia: A diagnostic clue in female pattern hair loss - 16/05/19
, David A. Whiting, MD bAbstract |
Background |
Focal atrichia is a common clinical finding in female pattern hair loss, the specificity and histologic findings of which need further clarification.
Objective |
To determine the frequency of focal atrichia in various types of hair loss and its histologic characteristics in female pattern hair loss.
Methods |
Part 1 of the study was a review of 250 consecutive female patients seen with hair loss for the presence of focal atrichia, and part 2 examined paired biopsy specimens from haired areas versus those from areas with focal atrichia in 18 subjects with female pattern hair loss.
Results |
Focal atrichia was seen in 46 of 104 of women with female pattern hair loss (44%), including 67% of those with the late-onset subtype versus 15% of those with the early-onset subtype, compared with in 3 of 146 of those with other hair disorders (2%). Biopsy findings of focal atrichia in female pattern hair loss showed primarily a more progressive miniaturization process than that of haired areas of the scalp.
Limitations |
Some women with female pattern hair loss may have had concomitant chronic telogen effluvium.
Conclusions |
When present, focal atrichia is a clinical clue to the diagnosis of female pattern hair loss, particularly the late-onset subtype.
Le texte complet de cet article est disponible en PDF.Key words : anagen, biopsy, female pattern hair loss, focal atrichia, telogen, terminal, vellus
Abbreviations used : ATE, CTE, EFPHL, FA, FFA, FPHL, LFPHL, MPHL, TE
Plan
| Supported by an unrestricted educational grant from Pharmacia and Co. |
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| Conflicts of interest: None declared. |
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| Previously presented in part at the World Congress of Hair Disorders, Tokyo, Japan, 2001, and at the World Congress of Hair Disorders, Vancouver, Canada, 2007. |
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| Reprints not available from the authors. |
Vol 80 - N° 6
P. 1538 - juin 2019 Retour au numéro
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