Anti-β2 Glycoprotein 1 and the Anti-phospholipid Syndrome - 18/08/11
, Kesavan Ravikumar, FRCSEd a, Susan I. O’Shea, MD b, Philip E. Cleary, FRCS, FRCOphth a
Inquiries to Pearse A. Keane, MD, MSc, Department of Ophthalmology, Cork University Hospital, Cork, IrelandRésumé |
Purpose |
To describe a patient who presented with bilateral retinal vascular occlusion and the use of anti-β2 glycoprotein 1 (GPI) antibody testing in the diagnosis of antiphospholipid syndrome.
Design |
Observational case report.
Methods |
Hematological investigations were performed on a 49-year-old man who presented with rapid onset of bilateral severe central retinal vein occlusion.
Results |
Lupus anticoagulant and anticardiolipin antibody testing was negative. Markedly raised titers of anti-β2 GPI antibodies were detected on two separate occasions.
Conclusions |
The raised titers of anti-β2 GPI antibodies were considered to strongly suggest an underlying diagnosis of the antiphospholipid syndrome.
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Vol 142 - N° 4
P. 701-702 - octobre 2006 Retour au numéro
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