Expanding the microcomedone theory and acne therapeutics: Propionibacterium acnes biofilm produces biological glue that holds corneocytes together to form plug - 19/08/11
Résumé |
The Propionibacterium acnes biofilm has previously been shown to exist via genomic studies and to make a biological glue which allows for adherence to follicular walls. This gylcocalyx polymer secreted by P acnes also finds its way into sebum composition where it causes the adhesiveness of keratinocytes leading to comedones. An appreciation of P acnes biofilms and secretions has implications in immunogenicity of the organism, clinical course of acne, and therapy for comedonal and inflammatory acne.
Le texte complet de cet article est disponible en PDF. Funding sources: None. |
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Conflicts of interest: None declared. |
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Reprints not available from the authors. |
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Correspondence to: cgbakb@aol.com. |
Vol 57 - N° 4
P. 722-724 - octobre 2007 Retour au numéroBienvenue sur EM-consulte, la référence des professionnels de santé.
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