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Journal of the American Academy of Dermatology
Volume 48, n° 2S
pages 35-38 (février 2003)
Doi : 10.1067/mjd.2003.114
Keratoacanthoma developing in sites of previous trauma: A report of two cases and review of the literature
 

Sean F. Pattee, BS, Nancy G. Silvis, MD
Section of Dermatology, University of Arizona College of Medicine. Tucson, Arizona 

Abstract

Keratoacanthoma is a common benign squamous neoplasm that only rarely progresses to metastatic carcinoma. The cause of keratoacanthoma is unclear; however, suspected causes include ultraviolet light, genetic factors, immunosuppression, chemical carcinogens, viruses, and trauma. Keratoacanthomas have been reported only rarely to arise in sites of previous trauma. We report 2 cases of keratoacanthomas arising shortly after episodes of cutaneous trauma and provide a review of the literature of similar cases previously reported. It is likely that an interaction exists between a variety of factors in the development of keratoacanthomas; however, it appears that a predilection exists for these lesions to arise in trauma sites. (J Am Acad Dermatol 2003;48:S35-8.)

The full text of this article is available in PDF format.

 This supplement is made possible through an unrestricted educational grant from Stiefel Laboratories to the American Academy of Dermatology.
 Reprint requests: Nancy G. Silvis, MD, 1501 N Campbell Ave, PO Box 245038, Tucson, AZ 85724. E-mail: spattee@u.arizona.edu
 0190-9622/2003/$30.00 + 0



© 2003  American Academy of Dermatology, Inc. Published by Elsevier Masson SAS@@#104157@@