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Journal of the American Academy of Dermatology
Volume 38, n° 5S
pages 815-819 (mai 1998)
Doi : 10.1016/S0190-9622(98)70465-7
Melanoma of the soft parts (clear cell sarcoma): A case report and review of the literature

Steven L. Mackey, LCDR, MC, USN, Jeanette Hebel, LT, MC, USNR, Mark W. Cobb, CDR, MC, USN
Department of Dermatology, National Naval Medical Center. Bethesda, Maryland 


Melanoma of the soft parts (clear cell sarcoma) is an uncommon soft tissue sarcoma that occurs in tendons and aponeuroses, usually of the lower extremity and is believed to be of neural crest origin. Although the exact histogenesis of this tumor is unknown and some controversy still exists, the generally accepted view is that it arises from neural crest cells that have the capability to produce melanin. Because melanin or melanosomes can be demonstrated in a majority of these cases, the term melanoma of the soft parts (MSP) has been advanced. These tumors commonly metastasize and have a very poor prognosis. (J Am Acad Dermatol 1998;38:815-9.)

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 This article is made possible through an educational grant from Ortho Dermatological.
 The opinions contained herein are the private views of the authors and are not to be construed as official or as reflecting the views of the Department of the Navy or the Department of Defense.
 Reprint requests: Steven Mackey, MD, Suite 208, Russell Hospital Medical Park Office, 3368 Highway 280, Alexander City, AL 35010.

© 1998  American Academy of Dermatology, Inc. Published by Elsevier Masson SAS@@#104157@@