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Journal of the American Academy of Dermatology
Volume 38, n° 6
pages 877-898 (juin 1998)
Doi : 10.1016/S0190-9622(98)70154-9
Cutaneous pseudolymphomas

Tanusin Ploysangam, MD*, Debra L. Breneman, MD, Diya F. Mutasim, MD
Cincinnati, Ohio 
From the Department of Dermatology, University of Cincinnati Medical Center 
*Dr. Ploysangam is currently affiliated with Biophile Corporation and Department of Dermatology, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand 


Cutaneous Pseudolymphoma refers to a heterogenous group of benign reactive T- or B-cell lymphoproliferative processes of diverse causes that simulate cutaneous lymphomas clinically and/or histologically. The inflammatory infiltrate is bandlike, nodular, or diffuse and is composed predominantly of lymphocytes with or without other inflammatory cells. Depending on the predominant cell type in the infiltrate, cutaneous pseudolymphomas are divided into T- and B-cell pseudolymphomas. Cutaneous T-cell pseudolymphomas include idiopathic cutaneous T-cell pseudolymphoma, lymphomatoid drug reactions, lymphomatoid contact dermatitis, persistent nodular arthropod-bite reactions, nodular scabies, actinic reticuloid, and lymphomatoid papulosis. Cutaneous B-cell pseudolymphomas include idiopathic lymphocytoma cutis, borrelial lymphocytoma cutis, tattoo-induced lymphocytoma cutis, post-zoster scar lymphocytoma cutis, and some persistent nodular arthropod-bite reactions. This review attempts to discuss current aspects of the classification, pathogenesis, clinical spectrum, histopathologic and immunohistochemical diagnosis, and laboratory investigations for clonality in the various types of cutaneous pseudolymphomas. (J Am Acad Dermatol 1998;38:877-905.) Learning Objective: At the conclusion of this learning activity, participants should understand the current classification, diagnostic criteria, and modern techniques used in the differentiation of cutaneous pseudolymphomas from cutaneous lymphomas.

The full text of this article is available in PDF format.

 Reprint requests: Diya F. Mutasim, MD, University Hospital, Department of Dermatology, A-Pavilion, 3rd Floor, 234 Goodman Ave., Cincinnati, OH 45267-0523.
 0190-9622/98/$5.00 + 0   16/2/88408

© 1998  American Academy of Dermatology, Inc. Published by Elsevier Masson SAS@@#104157@@