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Joint Bone Spine
Volume 74, n° 4
pages 382-384 (juillet 2007)
Doi : 10.1016/j.jbspin.2006.10.008
Received : 29 August 2006 ;  accepted : 18 October 2006
Thoracic spinal cord compression indicating Wegener's granulomatosis in a patient with a previous presumptive diagnosis of microscopic polyangiitis

Claude Bachmeyer a, , Pascale Cervera b, Béatrice Marro c, Wafa Ammouri a, Eric Bouvard a, Pascal Favrole d, Frédéric Jacquot e, Gilles Grateau a
a Service de Médecine Interne, CHU Tenon (AP-HP), 4 rue de la Chine, 75020 Paris, France 
b Service d'Anatomie et de Cytologie Pathologiques, CHU Saint-Antoine (AP-HP), Paris, France 
c Service de Radiologie, CHU Tenon (AP-HP), Paris, France 
d Service de Neurologie, CHU Tenon (AP-HP), Paris, France 
e Service d'Orthopédie, CHU Saint-Antoine (AP-HP), Paris, France 

Corresponding author. Tel.: +33 1 56 01 60 77; fax: +33 1 56 01 70 82.

Neurological signs are observed in 20-50% of cases of Wegener's granulomatosis consisting of peripheral and cranial neuropathy, and central nervous system involvement during the disease and rarely as initial symptom.

We report here a case of thoracic spinal cord compression due to dural masses in a patient with a previous presumptive diagnosis of microscopic polyangiitis indicating Wegener's granulomatosis on histological examination.

No other site of involvement was found. Slight clinical improvement was observed under immunosuppressive treatment probably because of spinal cord vessels lesions.

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Keywords : Wegener's granulomatosis, Thoracic spinal cord compression, p-ANCA

© 2007  Elsevier Masson SAS. All Rights Reserved.