Optimal selection is critical in patients with peritoneal carcinomatosis (PC) in whom curative cytoreductive surgery can be anticipated. 18F-FDG-PET/CT may result in false-positive findings that may eliminate patients for whom cytoreductive surgery would be beneficial.
To determine the rate of false-positive findings on 18F-FDG-PET/CT and clarify their causes in patients with suspected PC from colorectal cancer.
A retrospective analysis of 37 patients with suspected PC from colorectal cancer who had 18F-FDG-PET/CT before cytoreductive surgery was performed to determine the rate and the causes of false-positive findings. 18F-FDG-PET/CT was considered falsely positive when no tumor was found at surgery, histopathological analysis and follow-up.
False-positive findings were observed in four patients, yielding a 11% (95%CI: 3–25%) false-positive rate on a per-patient basis. The causes of false-positives were elucidated in two patients (surgical mesh after umbilical hernia repair and one foreign body granuloma).
False-positive findings on 18F-FDG-PET/CT are observed in 11% of patients with suspected PC from colorectal cancer. Familiarity with false-positive findings would result in more accurate selection of patients candidates to cytoreductive surgery.El texto completo de este artículo está disponible en PDF.
Keywords : 18F-FDG-PET/CT, Peritoneal carcinomatosis, False-positive findings, Imaging, Colorectal cancer, HIPEC, Hyperthermic intraperitoneal chemotherapy
Vol 152 - N° 5P. 285-291 - novembre 2015 Regresar al número
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