Cerebrovascular reactivity in the caudate nucleus, lentiform nucleus and thalamus in patients with carotid artery disease - 09/03/17
Bienvenido a EM-consulte, la referencia de los profesionales de la salud.
El acceso al texto completo de este artículo requiere una suscripción.
| páginas | 8 |
| Iconografías | 3 |
| Vídeos | 0 |
| Otros | 0 |
Summary |
Background and purpose |
To assess the effect of unilateral large vessel disease upon the cerebral hemodynamic autoregulatory status in the basal ganglia of patients with steno-occlusive internal carotid artery (ICA) disease.
Materials and methods |
Twenty-five healthy volunteers and 38 patients with a unilateral symptomatic steno-occlusive ICA lesion and were investigated; 20 with a stenosis >50% and 18 with an occlusion. Cerebral blood flow (CBF) and cerebrovascular reactivity (CVR) were assessed with pseudo-continuous arterial spin labeling (ASL) magnetic resonance (MR) imaging before and after administration of acetazolamide.
Results |
When compared to controls, the CVR in patients with ICA stenosis was significantly lower in the middle cerebral artery (MCA) territory (P<0.05), and in the caudate (P<0.05) and lentiform nucleus (P<0.05) of the hemisphere ipsilateral to the stenosis. The CVR in the caudate nucleus contralateral to the stenosis was significantly lower (P<0.05) as well. In patients with ICA occlusion, the CVR in the hemisphere ipsilateral to the occlusion as well as in the contralateral hemisphere was significantly lower in the MCA territory (P<0.05), the caudate (P<0.05) and lentiform nucleus (P<0.05), and in the thalamus (P<0.05).
Conclusion |
Perfusion ASL MR imaging shows impaired cerebral hemodynamic autoregulation of the basal ganglia in patients with steno-occlusive ICA disease both in the hemisphere ipsilateral as well as in the hemisphere contralateral to the stenosis or occlusion.
El texto completo de este artículo está disponible en PDF.Keywords : Magnetic resonance imaging, Perfusion, Cerebrovascular reactivity, Carotid artery disease
Abbreviations : ASL, CBF, CVR, ICA, MCA, RF, ROI, SEM
Esquema
Vol 44 - N° 2
P. 143-150 - mars 2017 Regresar al número
Artículo precedente
- Perianeurysmal edema: Prevalence, risk factors and clinical significance
- Lauren Wallaert, Sebastien Soize, Tom De Beule, Catherine Tomas, Laurent Pierot
- Dominant vertebral artery status and functional outcome after endovascular therapy of symptomatic basilar artery occlusion
- Jun Young Chang, Seunguk Jung, Cheolkyu Jung, Hee-Joon Bae, Oki Kwon, Moon-Ku Han
Bienvenido a EM-consulte, la referencia de los profesionales de la salud.
El acceso al texto completo de este artículo requiere una suscripción.
Bienvenido a EM-consulte, la referencia de los profesionales de la salud.
La compra de artículos no está disponible en este momento.
¿Ya suscrito a @@106933@@ revista ?