The anti-dermatophyte activity of Zataria multiflora essential oils - 06/06/17
, R. HeidaryTabar, E. MahdizadehBienvenido a EM-consulte, la referencia de los profesionales de la salud.
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Summary |
Objective |
Dermtophytes are a group of pathogenic fungi and the major cause of dermatophytosis in humans and animals. Fighting dermatophytes by natural essential oils is one important issue in new researches.
Materials and methods |
In this investigation, we evaluated the anti-dermatophyte activities of three samples of Z. multiflora essential oils against dermatophytes along with analysis of chemical compositions of the essential oils and their anti-elastase activities on elastase production in dermatophytes.
Results |
Carvacrol (1.5–34.4%), thymol (25.8–41.2%), carvacrol methyl ether (1.9–28.3%) and p-cymene (2.3–8.3%) were the main components of Z. multiflora essential oils. Z. multiflora essential oils (100ppm) inhibited the mycelium growth of dermatophytes (6±1.7–47.0±1.4%) and had the minimal inhibitory concentration (MIC) and minimal fungicidal concentration (MFC) values of 0.03–0.25μl/ml against dermatophytes. Essential oils inhibited elastase produced in dermatophytes and pure porcine elastase.
Conclusion |
Z. multiflora essential oils can be used as natural anti-dermatophyte agent for fighting dermatophytes in further preclinical and clinical studies.
El texto completo de este artículo está disponible en PDF.Keywords : Zataria multiflora, Essential oil, Dermatophyte, Elastase, Antifungal
Esquema
Vol 27 - N° 2
P. 232-237 - juin 2017 Regresar al número
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Bienvenido a EM-consulte, la referencia de los profesionales de la salud.
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