Widespread flat warts associated with human papillomavirus type 5: A cutaneous manifestation of human immunodeficiency virus infection - 12/10/17

Doi : 10.1016/0190-9622(90)70318-C

Neil S. Prose, MD ^{^{a
From the Department of Dermatology, State University of New York-Health Science Center at Brooklyn},}^{^{b
From the Department of Pediatrics, State University of New York-Health Science Center at Brooklyn},}^⁎, Christina von Knebel-Doeberitz, MD ^{^{c
From the Department of Pathology, State University of New York-Health Science Center at Brooklyn}}, Sheryl Miller, MD ^{^{a
From the Department of Dermatology, State University of New York-Health Science Center at Brooklyn}}, Peter B. Milburn, MD ^{^{a
From the Department of Dermatology, State University of New York-Health Science Center at Brooklyn}}, Edward Heilman, MD ^{^{a
From the Department of Dermatology, State University of New York-Health Science Center at Brooklyn},}^{^{d
the Institut fur Virologie, Deutsches Krebsforschungszentrum, Heidelberg.}}
¹ Brooklyn, New York, USA
² Heidelberg, West Germany

^*Reprint requests: Neil S. Prose, MD, Pediatric Dermatology, Box 3252, Duke University Medical Center, Durham, NC 27710.

Abstract

Numerous flat and tinea versicolor—like warts developed on the face, trunk, and upper extremities of a 10-year-old boy with human immunodeficiency virus infection. Nucleic acid analysis of involved skin revealed human papillomavirus type 5, which has sometimes been associated with epidermodysplasia verruciformis. This human papillomavirus type has also been described in patients with common variable immunodeficiency and dyskeratosis congenita and in renal allograft recipients. Human immunodeficiency virus infection should be added to the list of immune-related disorders that predispose to widespread fiat warts.

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