Diagnostic accuracy of point shear wave elastography in the detection of portal hypertension in pediatric patients - 08/03/18
Abstract |
Purpose |
The purpose of this study was to determine the usefulness of point shear wave elastography (p-SWE) of the liver and spleen for the detection of portal hypertension in pediatric patients.
Materials and methods |
The study consisted of 38 healthy children and 56 pediatric patients with biopsy-proven liver disease who underwent splenic and liver p-SWE. The diagnostic performance of p-SWE in detecting clinically significant portal hypertension was assessed using receiver operating characteristic (ROC) curves.
Results |
Reliable measurements of splenic and liver stiffness with p-SWE were obtained in 76/94 (81%) and 80/94 patients (85%), respectively. The splenic stiffness was highest in the portal hypertension group (P<0.01). At ROC curve analysis, the area under the curve in the detection of portal hypertension was lower for splenic p-SWE than for liver p-SWE (0.906 vs. 0.746; P=0.0239). The cut-off value of splenic p-SWE for portal hypertension was 3.14m/s, with a specificity of 98.59% and a sensitivity of 68.18%. The cut-off value of liver p-SWE for portal hypertension was 2.09m/s, with a specificity of 80.28% and a sensitivity of 77.27%.
Conclusion |
In pediatric patients, p-SWE is a reliable method for detecting portal hypertension. However, splenic p-SWE is less accurate than liver p-SWE for the diagnosis of portal hypertension.
El texto completo de este artículo está disponible en PDF.Keywords : Point shear wave elastography (p-SWE), Pediatric, Portal hypertension, Spleen, Liver
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Vol 99 - N° 3
P. 151-156 - mars 2018 Regresar al númeroBienvenido a EM-consulte, la referencia de los profesionales de la salud.