Diagnostic assessment of magnetic resonance imaging for patients with intralabyrinthine schwannoma: A systematic review - 15/09/20

Doi : 10.1016/j.neurad.2020.08.002

Se Jin Cho ^a, Byung Se Choi ^a,⁎ , Yun Jung Bae ^a, Jae-Jin Song ^b, Ja-Won Koo ^b, Ji-Soo Kim ^c, Sung Hyun Baik ^a, Leonard Sunwoo ^a, Jae Hyoung Kim ^a
^a Department of Radiology, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam, Republic of Korea
^b Department of Otorhinolaryngology-Head and Neck Surgery, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam, Republic of Korea
^c Department of Neurology, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam, Republic of Korea

^⁎Corresponding author.

En prensa. Pruebas corregidas por el autor. Disponible en línea desde el Tuesday 15 September 2020
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Graphical abstract

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Highlights

•	MRI is the technique of choice in detection and estimation of extent of ILS.
•	MRI is useful for pre-surgical planning and conservative monitoring of ILS.
•	MRI has acceptable diagnostic performance for ILS.

El texto completo de este artículo está disponible en PDF.

Abstract

Objectives

Recent advancements in high-resolution imaging have improved the diagnostic assessment of magnetic resonance imaging (MRI) for intralabyrinthine schwannoma (ILS). This systematic review aimed to evaluate the diagnostic performance of MRI for patients with ILS.

Methods

Ovid-MEDLINE and EMBASE databases were searched for related studies on the diagnostic performance of MRI for patients with ILS published up to February 10, 2020. The primary endpoint was the diagnostic performance of MRI for ILS. The quality of the enrolled studies was assessed using tailored questionnaires and the Quality Assessment of Diagnostic Accuracy Studies-2 criteria.

Results

Overall, 6 retrospective studies that included 122 patients with ILS from a parent population of 364 were included. The sample size, parent population and its composition, reference standard, detailed parameters of MRI, and even the diagnostic methods varied between the studies. The studies had moderate quality. The sensitivity of combination of T2WI and CE-T1WI was over 90%. Relative sensitivity of T2WI comparative to CE-T1WI ranged from 62% to 100%, and the specificity were 100%.