The first parent-child diagnosis of a multifocal squamous odontogenic tumor: A case report - 05/12/20
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Abstract |
Squamous odontogenic tumors (SOT) are rare, benign, odontogenic neoplasms of the jaws. The sporadically reported cases with multifocal SOTs seem to have a marked predilection for younger African American patients. In this case report a 14-year-old Caucasian male presented with swelling of the vestibular alveolar process, slight tooth divergence, and mobility. A multifocal squamous odontogenic tumor was diagnosed and subsequently treated twice with surgical enucleation. Two and a half years earlier his mother was diagnosed and treated for a similar multifocal SOT. Next-Generation-Sequencing targeted resequencing mutational analysis of the maternal surgical specimens was performed. No potential causal mutation could be identified. Postoperative follow-up of the patient showed no recurrence of the SOT after 2 years. This case report substantiates the possibility of a familial relationship in (multifocal) SOT, possibly changing current ideas concerning the etiology and treatment of these neoplasms.
El texto completo de este artículo está disponible en PDF.Keywords : Squamous odontogenic tumor, SOT, Multifocal SOT, Odontogenic, Parent-child relation, Case report
Esquema
Bienvenido a EM-consulte, la referencia de los profesionales de la salud.
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