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Emergence agitation after the cleft lip or palate surgery in pediatric patients: a prospective study - 21/12/20

Doi : 10.1016/j.jormas.2020.11.006 
Yongle Shi, Xiufeng Zhang, Yan Sun, Erning Mei, Xueli Wan, Li Tian
 State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & Dept. of Post Anesthesia Care Unit, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China 

Corresponding author.
En prensa. Pruebas corregidas por el autor. Disponible en línea desde el Monday 21 December 2020
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Abstract

Objective

The pediatric patients after the cleft lip or palate surgery have high incidences of postoperative complications. Emergence agitation is a common complication. It is also a mild complication compared with lingual swelling and other airway-related complications, which are more often expected in children. However, it can cover signs of hypoxic episodes that appear immediately after surgery, because enough monitoring of an agitated child is not possible. The study aimed to discuss the occurrence of EA after cleft lip or palate surgery in pediatric patients, and further to provide a basis for later interventions.

Methods

This prospective study included 214 patients aged 3 months to 6 years old at a tertiary stomatological teaching hospital. We calculated the EA scores for every patient when they entered PACU, were in PACU, and left from PACU, and the score ranges from 1 to 5 point. The patients occurred agitation if they scored from 3 to 5 on the 5-point scale, and the patients needed medication and care if they had a score of 4 or 5.

Result

The results showed that the EA scores of 69.63% (n = 149) among patients were 3 or higher when they entered PACU, 40.65% (n = 87) were 3 or higher when they were in PACU, and 21.03% (n = 45) were 3 or higher when they left from PACU. Whether they are children with cleft lip, cleft palate, or horizontal cleft, the EA scores had a significant difference among different timings when entering PACU, in PACU, and leaving PACU (P = 0.000). Further comparison showed that the EA score of patients was the highest when entering PACU, and the lowest when leaving PACU. A significant difference in the EA scores was found among the patients with cleft lip, cleft palate, and horizontal cleft when they were in PACU (P = 0.024), further comparison showed that the EA score of the patients with cleft lip was lower than patients with cleft palate or horizontal cleft. While there were no statistical differences in the EA scores among the patients with cleft lip, cleft palate, and horizontal cleft when they entered PACU and left from PACU (P > 0.05).

Conclusion

Children had a high incidence of EA after cleft lip or cleft palate or horizontal cleft surgery, especially when they entered PACU. Children after cleft palate and horizontal cleft surgery had higher incidences of EA than cleft lip surgery when they were in PACU.

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Keywords : Cleft lip, Cleft palate, Emergence agitation (EA), General anesthesia (GA), Postanesthetic care unit (PACU)


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