PULMONARY ARTERIAL HYPERTENSION IN SYSTEMIC SCLEROSIS - 03/02/21
Doi : 10.1016/j.lpm.2021.104062
Benoît Lechartier 1, Marc Humbert 2, 3, 4
1 Department of Respiratory Medicine, Lausanne University Hospital, Lausanne, Switzerland
2 Université Paris-Saclay, Faculty of Medicine, Le Kremlin-Bicêtre, France
3 INSERM UMR_S 999 (Pulmonary Hypertension: Pathophysiology and Novel Therapies), Hôpital Marie Lannelongue, Le Plessis-Robinson, France
4 Assistance Publique - Hôpitaux de Paris (AP-HP), Department of Respiratory and Intensive Care Medicine, French Pulmonary Hypertension Reference Center, Hôpital Bicêtre, Le Kremlin-Bicêtre, France
En prensa. Manuscrito Aceptado.
Disponible en línea desde el Wednesday 03 February 2021
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SUMMARY |
Pulmonary arterial hypertension (PAH) is a frequent and severe complication of systemic sclerosis (SSc) due to combined vasculopathy and fibrogenesis. Early diagnosis and treatment are highly challenging in SSc-PAH and require referral to a n expert PAH centre. Diagnostic algorithms evolved in the last decade. Novel therapeutic options notably targeting pulmonary vascular remodeling are needed.
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Publicado por Elsevier Masson SAS.
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