Interpretation of fluid-attenuated inversion recovery vascular hyperintensity in stroke - 05/02/21

Doi : 10.1016/j.neurad.2021.01.009

Kyung-Yul Lee ^a, Jin Woo Kim ^b, Mina Park ^b, Sang Hyun Suh ^b, Sung Jun Ahn ^b,⁎
^a Department of Neurology, Gangnam Severance Hospital, Yonsei University, College of Medicine, Seoul, Korea
^b Department of Radiology, Gangnam Severance Hospital, Yonsei University, College of Medicine, Seoul, Korea

^⁎Corresponding author at: Department of Radiology, Gangnam Severance Hospital, Yonsei University, College of Medicine, 211 Eonju-ro, Gangnam-gu, Seoul 135-720, Korea.Department of RadiologyGangnam Severance HospitalYonsei UniversityCollege of Medicine211 Eonju-ro, Gangnam-guSeoul135-720Korea

En prensa. Pruebas corregidas por el autor. Disponible en línea desde el Friday 05 February 2021
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Graphical abstract

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Abstract

Fluid-attenuation inversion recovery (FLAIR) vascular hyperintensity (FVH) is a common presentation on brain magnetic resonance images of patients with acute ischemic stroke. This sign is known as a sluggish collateral flow. Although FVH represents the large ischemic penumbra and collateral circulation, the clinical significance of FVH has not been established. Varying protocols for FLAIR, treatment differences, and heterogeneity of endpoints across studies have complicated the interpretation of FVH in patients with acute stroke. In this review article, we describe the mechanism of FVH, as well as its association with functional outcome, perfusion-weighted images, and large artery stenosis. In addition, we review the technological variables that affect FVH and discuss the future perspectives.

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Keywords : FLAIR, FLAIR vascular hyperintensity (FVH), Stroke, MRI, Perfusion, Collateral