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COVID-19 outpatient management: Shorter time to recovery in Healthcare workers according to an electronic daily symptoms assessment - 20/02/21

Doi : 10.1016/j.medmal.2020.10.001 
E. Breugnon a, H. Thollot b, A. Fraissenon c, F. Saunier a, R. Labetoulle a, S. Pillet d, e, F. Lucht a, e, f, P. Berthelot a, e, f, E. Botelho-Nevers a, e, f, A. Gagneux-Brunon a, e, f,
a Department of Hygiene and Infectious Diseases, University Hospital of Saint-Etienne, 42055 Saint-Etienne Cedex 2, France 
b Department of Public health and biostatistics, University Hospital of Saint-Etienne, Saint-Etienne, France 
c Department of Radiology, University Hospital of Saint-Etienne, Saint-Etienne, France 
d Laboratory of Microbiology and Hygiene, University Hospital of Saint-Etienne, Saint-Etienne, France 
e Groupe Immunité des Muqueuses et Agents Pathogènes, Université Jean Monnet, Université de Lyon, Saint-Etienne, France 
f CIC-INSERM 1408, University Hospital of Saint-Etienne, Saint-Etienne, France 

Corresponding author at: Department of Hygiene and Infectious Diseases, University Hospital of Saint-Etienne, 42055 Saint-Etienne Cedex 2, France.Department of Hygiene and Infectious Diseases, University Hospital of Saint-EtienneSaint-Etienne Cedex 242055France

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Highlights

COVID-19 outcomes are favorable in patients eligible for outpatient care.
Individuals with mild symptoms of COVID-19 could be treated at home.
The median time to recovery was 9 days after symptoms onset.
Median time to recovery from symptoms onset was shorter in healthcare workers than in non-healthcare workers.
At day 7, more than the half of the individuals reported no symptoms.

El texto completo de este artículo está disponible en PDF.

Abstract

Objectives

Our aim is to compare the course of the disease between healthcare workers (HCWs) and non-HCWs suffering from covid-19 and eligible for outpatient management.

Methods

Single-center prospective cohort of outpatients with covid-19, diagnosed between the 10th March and the 2nd April, 2020 with a daily collection of symptoms by an on-line auto-questionnaire.

Results

A total of 186 patients were included (median age, 41 years [interquartile range, 19–78 years]; 74.2% female), of whom 132 (71%) were HCWs. The median follow-up after symptom onset was 14 (min 4–max 24) days. HCWs were significantly younger than non-HCWs (median age 40.3 years vs. 47.2 years [P<0.005]), and 81.8% were women. Four patients (2.2%) were hospitalized including one HCW. The median time to recovery was 9 days after symptom onset (95% CI 8-11) in the global population and respectively 8 (95% CI 8–9) and 13 (95% CI 11–15) days in HCWs and in non-HCWs (P<0.005). After adjusting for age, co-morbidities, and gender, the instantaneous risk ratio for symptom absence in HCWs was 1.76 compared with non-HCWs (95% CI [1.16–2.67], P=0.037).

Conclusion

HCWs suffering from covid-19 had favorable outcomes and had a shorter time to recovery than non HCWs.

El texto completo de este artículo está disponible en PDF.

Keywords : Covid-19, Outpatient, Healthcare workers, Healthcare professionals, Outcomes


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© 2020  Publicado por Elsevier Masson SAS.
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Vol 51 - N° 1

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