Invasive Aspergillosis associated with Covid-19: A word of caution - 08/05/21
, Theophile Cocherie b , Odile Eloy b , Stéphane Legriel a, d , Jean-Pierre Bedos a , Christelle Simon c , Stephanie Marque-Juillet b , Alexis Ferré a , Fabrice Bruneel a
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Highlights |
• | Invasive pulmonary aspergillosis associated with Covid-19 has been reported. |
• | Incidence of aspergillosis associated with Covid-19 is still to be determined. |
• | Means of diagnosis for pulmonary aspergillosis in Covid-19 need to be evaluated. |
• | Multiple definitions for probable invasive pulmonary aspergillosis exist. |
• | A consensus definition for Covid-19-associated pulmonary aspergillosis is needed. |
Abstract |
Introduction |
Invasive pulmonary aspergillosis is a well-known complication of acute respiratory distress syndrome, the most serious manifestation of COVID-19. Four recent studies have reported its incidence among ICU COVID-19 patients. However, they do not share the same case definition, and have provided conflicting results. In this paper we have aimed at reported the incidence of invasive pulmonary aspergillosis for COVID-19 patients in our ICU, and at comparing the different definitions in order to assess their respective relevance.
Methods |
Retrospective cohort study of critically ill patients with severe COVID-19 requiring ICU management between 1st March and 30th April 2020.
Results |
Our results showed significantly lower incidence of invasive pulmonary aspergillosis (1.8%;1/53), compared to three out of four previous studies, and wide variation in the numbers of cases with regard to the different definitions.
Conclusion |
Large-scale studies are needed for a better definition and a more accurate estimation of invasive pulmonary aspergillosis coinfection during COVID-19.
El texto completo de este artículo está disponible en PDF.Keywords : COVID-19, Aspergillosis, Coronavirus Infections/pathology, Pulmonary Aspergillosis/diagnosis
Esquema
Vol 51 - N° 4
P. 383-386 - juin 2021 Regresar al número
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