Change in pain severity with open label venlafaxine use in patients with a depressive symptomatology: An observational study in primary care - 17/04/08
, Martin Traber b, 1 , Martin Gerber c , Roland von Känel a, 2 
Corresponding author. Tel.: +41 31 632 20 19; fax: +41 31 382 11 84.Bienvenido a EM-consulte, la referencia de los profesionales de la salud.
El acceso al texto completo de este artículo requiere una suscripción.
| páginas | 9 |
| Iconografías | 2 |
| Vídeos | 0 |
| Otros | 0 |
Abstract |
Purpose |
Venlafaxine has shown benefit in the treatment of depression and pain. Worldwide data are extensively lacking investigating the outcome of chronic pain patients with depressive symptoms treated by venlafaxine in the primary care setting. This observational study aimed to elucidate the efficacy of venlafaxine and its prescription by Swiss primary care physicians and psychiatrists in patients with chronic pain and depressive symptomatology.
Subjects and methods |
We studied 505 patients with depressive symptoms suffering from chronic pain in a prospective naturalistic Swiss community based observational trial with venlafaxine in primary care. These patients have been treated with venlafaxine by 122 physicians, namely psychiatrists, general practitioners, and internists.
Results |
On average, patients were treated with 143±75mg (0–450mg) venlafaxine daily for a follow-up of three months. Venlafaxine proved to be beneficial in the treatment of both depressive symptoms and chronic pain.
Discussion |
Although side effects were absent in most patients, physicians might have frequently omitted satisfactory response rate of depression by underdosing venlafaxine. Our results reflect the complexity in the treatment of chronic pain in patients with depressive symptoms in primary care.
Conclusion |
Further randomized dose-finding studies are needed to learn more about the appropriate dosage in treating depression and comorbid pain with venlafaxine.
El texto completo de este artículo está disponible en PDF.Keywords : Pain, Unipolar depression, Antidepressant, Psychiatry in Europe, Switzerland, Primary care, Venlafaxine, Clinical care
Esquema
Vol 23 - N° 3
P. 178-186 - avril 2008 Regresar al número
Artículo precedente
- Awareness of metabolic concerns in patients with bipolar disorder: A survey of European psychiatrists
- Michael Bauer, Yves Lecrubier, Trisha Suppes
- Obsessive–compulsive disorder: Influence of age at onset on comorbidity patterns
- Maria Alice de Mathis, Maria Conceição do Rosario, Juliana Belo Diniz, Albina Rodrigues Torres, Roseli Gedanki Shavitt, Ygor Arzeno Ferrão, Victor Fossaluza, Carlos Alberto de Bragança Pereira, Eurípedes Constantino Miguel
Bienvenido a EM-consulte, la referencia de los profesionales de la salud.
El acceso al texto completo de este artículo requiere una suscripción.
Bienvenido a EM-consulte, la referencia de los profesionales de la salud.
La compra de artículos no está disponible en este momento.
¿Ya suscrito a @@106933@@ revista ?