Obsessive–compulsive disorder: Influence of age at onset on comorbidity patterns - 17/04/08
, Maria Conceição do Rosario a, d, f, Juliana Belo Diniz a, d, Albina Rodrigues Torres b, d, Roseli Gedanki Shavitt a, d, Ygor Arzeno Ferrão c, d, Victor Fossaluza a, e, Carlos Alberto de Bragança Pereira e, Eurípedes Constantino Miguel a, d
Corresponding author. Department of Psychiatry, University of Sao Paulo Medical School, Rua Dr. Ovídio Pires de Campos, 785, Room 7, 05403-010 São Paulo, SP, Brazil. Tel.: +55 11 3069 7896; fax: +55 11 3069 7895.Bienvenido a EM-consulte, la referencia de los profesionales de la salud.
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Abstract |
Purpose |
This study investigates the influence of age at onset of OCS on psychiatric comorbidities, and tries to establish a cut-off point for age at onset.
Methods |
Three hundred and thirty OCD patients were consecutively recruited and interviewed using the following structured interviews: Yale-Brown Obsessive Compulsive Scale; Yale Global Tic Severity Scale and the Structured Clinical Interview for DSM-IV. Data were analyzed with regression and cluster analysis.
Results |
Lower age at onset was associated with a higher probability of having comorbidity with tic, anxiety, somatoform, eating and impulse–control disorders. Longer illness duration was associated with lower chance of having tics. Female gender was associated with anxiety, eating and impulse–control disorders. Tic disorders were associated with anxiety disorders and attention-deficit/hyperactivity disorder. No cut-off age at onset was found to clearly divide the sample in homogeneous subgroups. However, cluster analyses revealed that differences started to emerge at the age of 10 and were more pronounced at the age of 17, suggesting that these were the best cut-off points on this sample.
Conclusions |
Age at onset is associated with specific comorbidity patterns in OCD patients. More prominent differences are obtained when analyzing age at onset as an absolute value.
El texto completo de este artículo está disponible en PDF.Keywords : Obsessive–compulsive disorder, Age at onset, Comorbidity, Early onset, Late onset
Esquema
Vol 23 - N° 3
P. 187-194 - avril 2008 Regresar al número
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Bienvenido a EM-consulte, la referencia de los profesionales de la salud.
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