COVID-19 and Candida duobushaemulonii superinfection: A case report - 31/08/21
, Maria Chalfoun c, George Araj d, Abdul Rahman Bizri a
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Abstract |
Introduction |
Critically ill COVID-19 patients are at high risk for nosocomial bacterial and fungal infections due to several predisposing factors such as intensive care unit stay, mechanical ventilation, and broad-spectrum antibiotics. Data regarding multidrug resistant (MDR) Candida species in COVID-19 patients is scarce, and nonexistent regarding Candida duobushaemulonii superinfections.
Case description |
A 34-year-old male presented to our institution with acute respiratory distress syndrome (ARDS) due to COVID-19 infection and developed Candida duobushaemulonii fungemia after multiple courses of antibiotics and prolonged mechanical ventilation. He died after recurrent pneumothorax led to respiratory failure and cardiac arrest.
Discussion |
Bacterial and fungal infections are common complications of viral pneumonia in critically ill patients. Data regarding these infections in COVID-19 patients has been poorly studied with only a few cases reporting secondary infection, mostly without identifying specific pathogens. Prolonged hospital stays, invasive interventions (central venous catheter, mechanical ventilation), and the use of broad-spectrum antibiotics in COVID-19 infections could carry a high risk of bacterial and/or fungal superinfections.
Conclusion |
Strategies to improve outcome in COVID-19 ICU patients should include early recognition of candidemia and appropriate antifungal therapy.
El texto completo de este artículo está disponible en PDF.Keywords : COVID-19, Candida duobushaemulonii, ICU, Multidrug resistance, Mechanical ventilation, Broad-spectrum antibiotics
Abbreviations : rtPa, DTA, COVID-19, ARDS, S. maltophilia, TMP-SMX, MIC, CAUTI, VAP
Esquema
Vol 31 - N° 3
Artículo 101168- septembre 2021 Regresar al número
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