Cinnamon and its possible impact on COVID-19: The viewpoint of traditional and conventional medicine - 09/10/21
, Zahra Taghipour a, Mehran Mirabzadeh Ardakani a, Mahdi Alizadeh Vaghasloo b, Mahdi Vazirian c, Sima Sadrai d
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Abstract |
The COVID-19 global epidemic caused by coronavirus has affected the health and other aspects of life for more than one year. Despite the current pharmacotherapies, there is still no specific treatment, and studies are in progress to find a proper therapy with high efficacy and low side effects. In this way, Traditional Persian Medicine (TPM), due to its holistic view, can provide recommendations for the prevention and treatment of new diseases such as COVID-19. The muco-obstruction of the airway, which occurs in SARS-CoV-2, has similar features in TPM textbooks that can lead us to new treatment approaches. Based on TPM and pharmacological studies, Cinnamomum verum (Darchini)'s potential effective functions can contribute to SARS-CoV-2 infection treatment and has been known to be effective in corona disease in Public beliefs. From the viewpoint of TPM theories, Cinnamon can be effective in SARS-CoV-2 improvement and treatment through its anti-obstructive, diuretic, tonic and antidote effects. In addition, there is pharmacological evidence on anti-viral, anti-inflammatory, antioxidant, organ-o-protective and anti-depression effects of Cinnamon that are in line with the therapeutic functions mentioned in TPM.Overall, Cinnamon and its ingredients can be recommended for SARS-CoV2 management due to multi-targeting therapies. This review provides basic information for future studies on this drug's effectiveness in preventing and treating COVID-19 and similar diseases.
El texto completo de este artículo está disponible en PDF.Graphical Abstract |
Highlights |
• | Theoretically Cinnamon can be effective on COVID19 due to anti-obstructive effect. |
• | evidences exert antiviral, anti-inflammatory, antioxidant functions of Cinnamon. |
• | organo-protective and antidepression effects ameliorate complications of COVID19. |
Abbreviations : ACE2, IL, TNF-α, TPM, COPD, COVID-19, SARS-CoV-2, ARDS, TMPRSS2, TLRs, TCA, LPS, ERK, p38 MAPK, JNK, ROS, BHT, GPx, CAT, SOD, EEC, QR, GSH, γ-GCS, TAPP, BAL, MDA, CK-MB, LDH, BUN, AST, ALT, ATI, PCNA, PCB2, PKC-a, MCP-1, VCAM-1, TBARS, PCO, iNOS, NAFLD, HOMA, FBS, TC, TG, LDL, GGT, IFN-γ, BCP, COX-2, ICU
Keywords : Cinnamomum verum, Cinnamon, COVID-19, Obstruction, Opener, Traditional Persian Medicine (TPM)
Esquema
Vol 143
Artículo 112221- novembre 2021 Regresar al número
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