Peritoneal recurrence of colorectal cancer with microsatellite instability: Is immunotherapy alone more effective than surgery? - 03/12/21
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Summary |
A 67-year-old man was treated with systemic chemotherapy and cytoreductive surgery for microsatellite instable (MSI), deficient mismatch repair (dMMR) right colonic cancer with peritoneal metastases. Disease was controlled only when anti-PD1 and anti-CTLA4 immune checkpoint inhibitors were introduced. The patient is in complete remission after five years of follow-up. First-line immunotherapy could have a central role in the management of patients with peritoneal recurrence from MSI/dMMR colorectal cancer even though amenable to surgical treatment.
El texto completo de este artículo está disponible en PDF.Keywords : Colonic adenocarcinoma, MSI, Peritoneal metastasis, Cytoreduction, Hyperthermic intraperitoneal chemotherapy, Immunotherapy, Anti PD-1/Anti-PDL1
Esquema
Bienvenido a EM-consulte, la referencia de los profesionales de la salud.
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