The role of magnetic resonance imaging in assessing the extent of tongue squamous cell carcinoma: A prospective cohort study - 24/04/22
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Abstract |
Purpose |
To assess the false-positive and false-negative MRI results in evaluating the extent of tongue squamous cell carcinoma.
Methods |
A prospective cohort series of 165 patients was enrolled to assess the false-positive and false-negative MRI results in evaluating the extent of tongue squamous cell carcinoma by comparing intraoperative tumor profile images and postoperative pathological sections. The differences between two-dimensional tumor margins were analyzed using Mimics 15.0 and Geomagic Control 16.0. A paired-samples t-test was used to analyze the agreement among MRI, intraoperative and pathological findings regarding the extent of tongue tumors. Multiple linear regression analysis was used to analyze associated factors.
Results |
The mean and maximum false-positive values of pathological specimens was 1.95±1.39 mm (95% limit of agreement (LoA) 1.70–2.14) and 3.21 mm, respectively; the false-negative value was 0.44±0.49 mm. The false-positive value of intraoperative specimens was 1.52±0.87 mm (95% LoA 1.36–1.64); the false-negative value was 0.35±0.20 mm. Tumor morphology (ulcer type) (p<0.01) and depth of invasion (DOI) (≤5 mm) (p<0.01) were significantly correlated with the false-positive values of intraoperative and pathology specimens.
Conclusion |
The false-positive values are important when judging the invasion margin of tongue cancer and forming MRI-based operative plans; the false-negative value was almost negligible.
El texto completo de este artículo está disponible en PDF.Keywords : Depth of invasion, Magnetic resonance imaging, Growth pattern, Tumor margin
Abbreviations : AJCC, DOI, MRI, DMP, DMI, DIP, LoA
Esquema
Bienvenido a EM-consulte, la referencia de los profesionales de la salud.
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