Optimal depth of sedation in critically ill patients is essential to prevent complications related to oversedation or undersedation. Current best practices aim for a calm, responsive state unless deep sedation is clinically indicated. Tools like the Richmond Agitation-Sedation Scale and others provide structured frameworks for assessing sedation and agitation levels. RASS is the most widely used due to its simplicity, reliability, and broad validation. Combining sedation scoring systems with feedback devices such as the Bispectral Index offers a multimodal strategy for sedation management. This dual approach is considered as best practice, balancing the strengths of behavioral scoring with objective monitoring.